Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators

Gehad Lotfy; Yasmine M. Abdel Aziz; Mohamed M. Said; El Sayed H. El Ashry; El Sayed H. El Tamany; Marwa M. Abu-Serie; Mohamed Teleb; Alexander Dömling; Assem Barakat

Bioorganic Chemistry (2021) - Comments
pubmed: 34794098 doi: 10.1016/j.bioorg.2021.105427 issn: 0045-2068 issn: 1090-2120

Gehad Lotfy, Yasmine M. Abdel Aziz, Mohamed M. Said, El Sayed H. El Ashry, El Sayed H. El Tamany, Marwa M. Abu-Serie, Mohamed Teleb, Alexander Dömling, Assem Barakat