The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance

Journal of Biological Chemistry (2012) - Comment
pubmed: 22556409 doi: 10.1074/jbc.m111.304626 issn: 0021-9258 issn: 1083-351x

Bao Hoang, Angelica Benavides, Yijiang Shi, Yonghui Yang, Patrick Frost, Joseph Gera, Alan Lichtenstein