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Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells
Molecular Pharmacology (2008) -
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pubmed: 18287248 doi: 10.1124/mol.107.041350 issn: 1521-0111 issn: 0026-895x
Yasunari Takada, Gautam Sethi, Bokyung Sung, Bharat B. Aggarwal
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American Society for Pharmacology & Experimental Therapeutics (ASPET)
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