The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2
Molecular Cell (2002) - Comments
pubmed: 12049732  issn: 1097-2765  doi: 10.1016/s1097-2765(02)00519-1 

Zhimin Lu, Shuichan Xu, Claudio Joazeiro, Melanie H Cobb, Tony Hunter