Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial

Alexander P J Vlaar; Martin Witzenrath; Pieter van Paassen; Leo M A Heunks; Bruno Mourvillier; Sanne de Bruin; Endry H T Lim; Matthijs C Brouwer; Pieter R Tuinman; José F K Saraiva; Gernot Marx; Suzana M Lobo; Rodrigo Boldo; Jesus A Simon-Campos; Alexander D Cornet; Anastasia Grebenyuk; Johannes M Engelbrecht; Murimisi Mukansi; Philippe G Jorens; Robert Zerbib; Simon Rückinger; Korinna Pilz; Renfeng Guo; Diederik van de Beek; Niels C Riedemann; Alexander P.J. Vlaar; Martin Witzenrath; Pieter van Paassen; Leo M.A. Heunks; Bruno Mourvillier; Sanne de Bruin; Endry H.T. Lim; Matthijs C. Brouwer; Pieter R. Tuinman; José Francisco K. Saraiva; Gernot Marx; Suzana Lobo; Rodrigo Boldo; Jesus Simon-Campos; Alexander D. Cornet; Anastasia Grebenyuk; Johannes Engelbrecht; Murimisi Mukansi; Philippe G. Jorens; Robert Zerbib; Simon Rückinger; Korinna Pilz; Renfeng Guo; Diederik van de Beek; Niels C. Riedemann; Pierre Bulpa; Fabio S. Taccone; Greet Hermans; Marc Diltoer; Michael Piagnerelli; Nikolaas De Neve; Antonio T. Freire; Felipe D. Pizzol; Anna Karolina Marinho; Victor H. Sato; Clovis Arns da Cunha; Mathilde Neuville; Jean Dellamonica; Djillali Annane; Antoine Roquilly; Jean Luc Diehl; Francis Schneider; Jean Paul Mira; Jean Baptiste Lascarrou; Luc Desmedt; Claire Dupuis; Carole Schwebel; Guillaume Thiéry; Matthias Gründling; Marc Berger; Tobias Welte; Michael Bauer; Ulrich Jaschinski; Klaus Matschke; Roberto Mercado-Longoria; Belinda Gomez Quintana; Jorge Alberto Zamudio-Lerma; Juan Moreno Hoyos Abril; Angel Aleman Marquez; Peter Pickkers; Luuk Otterspoor; Luis Hercilla Vásquez; Carlos Rafael Seas Ramos; Alejandro Peña Villalobos; Gonzalo Gianella Malca; Victoria Chávez; Victor Filimonov; Vladimir Kulabukhov; Pinak Acharya; Sjoerd A.M.E.G. Timmermans; Matthias H. Busch; Floor L.F. van Baarle; Rutger Koning; Liora ter Horst; Nora Chekrouni; Thijs M. van Soest; Marleen A. Slim; Lonneke A. van Vught; Rombout B.E. van Amstel; Sabine E. Olie; Ingeborg E. van Zeggeren; Marcel C.G. van de Poll; Claus Thielert; Dorothee Neukirchen

The Lancet Respiratory Medicine (2022) - Comments
pubmed: 36087611 doi: 10.1016/s2213-2600(22)00297-1 issn: 2213-2600 issn: 2213-2619

Alexander P J Vlaar, Martin Witzenrath, Pieter Van Paassen, Leo M A Heunks, Bruno Mourvillier, Sanne De Bruin, Endry H T Lim, Matthijs C Brouwer, Pieter R Tuinman, José F K Saraiva, Gernot Marx, Suzana M Lobo, Rodrigo Boldo, Jesus A Simon-Campos, Alexander D Cornet, Anastasia Grebenyuk, Johannes M Engelbrecht, Murimisi Mukansi, Philippe G Jorens, Robert Zerbib