Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

Maheshi N Ramasamy; Angela M Minassian; Katie J Ewer; Amy L Flaxman; Pedro M Folegatti; Daniel R Owens; Merryn Voysey; Parvinder K Aley; Brian Angus; Gavin Babbage; Sandra Belij-Rammerstorfer; Lisa Berry; Sagida Bibi; Mustapha Bittaye; Katrina Cathie; Harry Chappell; Sue Charlton; Paola Cicconi; Elizabeth A Clutterbuck; Rachel Colin-Jones; Christina Dold; Katherine R W Emary; Sofiyah Fedosyuk; Michelle Fuskova; Diane Gbesemete; Catherine Green; Bassam Hallis; Mimi M Hou; Daniel Jenkin; Carina C D Joe; Elizabeth J Kelly; Simon Kerridge; Alison M Lawrie; Alice Lelliott; May N Lwin; Rebecca Makinson; Natalie G Marchevsky; Yama Mujadidi; Alasdair P S Munro; Mihaela Pacurar; Emma Plested; Jade Rand; Thomas Rawlinson; Sarah Rhead; Hannah Robinson; Adam J Ritchie; Amy L Ross-Russell; Stephen Saich; Nisha Singh; Catherine C Smith; Matthew D Snape; Rinn Song; Richard Tarrant; Yrene Themistocleous; Kelly M Thomas; Tonya L Villafana; Sarah C Warren; Marion E E Watson; Alexander D Douglas; Adrian V S Hill; Teresa Lambe; Sarah C Gilbert; Saul N Faust; Andrew J Pollard; Jeremy Aboagye; Kelly Adams; Aabidah Ali; Elizabeth R. Allen; Lauren Allen; Jennifer L. Allison; Foteini Andritsou; Rachel Anslow; Edward H. Arbe-Barnes; Megan Baker; Natalie Baker; Philip Baker; Ioana Baleanu; Debbie Barker; Eleanor Barnes; Jordan R. Barrett; Kelly Barrett; Louise Bates; Alexander Batten; Kirsten Beadon; Rebecca Beckley; Duncan Bellamy; Adam Berg; Laura Bermejo; Eleanor Berrie; Amy Beveridge; Kevin Bewley; Else M. Bijker; Geeta Birch; Luke Blackwell; Heather Bletchly; Caitlin L. Blundell; Susannah R. Blundell; Emma Bolam; Elena Boland; Daan Bormans; Nicola Borthwick; Konstantinos Boukas; Thomas Bower; Francesca Bowring; Amy Boyd; Tanja Brenner; Phillip Brown; Charlie Brown-O'Sullivan; Scott Bruce; Emily Brunt; Jamie Burbage; Joshua Burgoyne; Karen R. Buttigieg; Nicholas Byard; I.C. Puig; Susana Camara; Michelangelo Cao; Federica Cappuccini; Melanie Carr; Miles W. Carroll; Paul Cashen; Ana Cavey; Jim Chadwick; Ruth Challis; D. Charles; J. Cho; L. Cifuentes; E. Clark; S. Collins; C.P. Conlon; N.S. Coombes; R. Cooper; C. Cooper; W.E.M. Crocker; S. Crosbie; D. Cullen; C.J. Cunningham; F. Cuthbertson; B.E. Damratoski; L. Dando; M.S. Datoo; C. Datta; H. Davies; S. Davies; E. Davis; J. Davis; D. Dearlove; T. Demissie; S. Di Marco; C. Di Maso; D. DiTirro; C. Docksey; T. Dong; F.R. Donnellan; N. Douglas; C. Downing; J. Drake; R. Drake-Brockman; R.E. Drury; S.J. Dunachie; C.J. Edwards; N.J. Edwards; O. El Muhanna; S.C. Elias; R.S. Elliott; M.J. Elmore; M.R. English; S. Felle; S. Feng; C. Ferreira Da Silva; S. Field; R. Fisher; C. Fixmer; K.J. Ford; J. Fowler; E. Francis; J. Frater; J. Furze; P. Galian-Rubio; C. Galloway; H. Garlant; M. Gavrila; F. Gibbons; K. Gibbons; C. Gilbride; H. Gill; K. Godwin; K. Gordon-Quayle; G. Gorini; L. Goulston; C. Grabau; L. Gracie; N. Graham; N. Greenwood; O. Griffiths; G. Gupta; E. Hamilton; B. Hanumanthadu; S.A. Harris; T. Harris; D. Harrison; T.C. Hart; B. Hartnell; L. Haskell; S. Hawkins; J.A. Henry; M.H. Herrera; D. Hill; J. Hill; G. Hodges; S.H.C. Hodgson; K. Horton; E. Howe; N. Howell; J. Howes; B. Huang; J. Humphreys; H. Humphries; P. Iveson; F. Jackson; S. Jackson; S. Jauregui; H. Jeffers; B. Jones; C.E. Jones; E. Jones; K. Jones; A. Joshi; R. Kailath; J. Keen; E.J. Kelly; D.M. Kelly; S. Kelly; Sarah Kelly; D. Kerr; L. Khan; A. Killen; J. Kinch; L.D.W. King; T.B. King; L. Kingham; P. Klenerman; J.C. Knight; D. Knott; S. Koleva; G. Lang; C.W. Larkworthy; J.P.J. Larwood; R.L. Law; A. Lee; K.Y.N. Lee; E.A. Lees; S. Leung; Y. Li; A.M. Lias; A. Linder; S. Lipworth; S. Liu; X. Liu; S. Lloyd; L. Loew; R. Lopez Ramon; M. Madhavan; D. Mainwaring; G. Mallett; K. Mansatta; S. Marinou; P. Marius; E. Marlow; P. Marriott; J.L. Marshall; J. Martin; S. Masters; J. McEwan; J. McGlashan; L. McInroy; N. McRobert; C. Megson; A.J. Mentzer; N. Mirtorabi; C. Mitton; M. Moore; M. Moran; E. Morey; R. Morgans; S.R. Morris; H. Morrison; G. Morshead; R. Morter; J. Muller; C. Munro; S. Murphy; P. Mweu; A. Noé; F.L. Nugent; K. O'Brien; D. O'Connor; B. Oguti; V. Olchawski; C. Oliveria; P.J. O'Reilly; P. Osborne; L. Owen; N. Owino; P. Papageorgiou; H. Parracho; H. Parsons; B. Patel; M. Patrick-Smith; Y. Peng; E. Penn; M.P. Peralta Alvarez; J. Perring; C. Petropoulos; D.J. Phillips; D. Pipini; S. Pollard; I. Poulton; D. Pratt; L. Presland; P. Proud; S. Provstgaard-Morys; S. Pueschel; D. Pulido; R. Rabara; K. Radia; D. Rajapaksa; F. Ramos Lopez; H. Ratcliffe; S. Rayhan; B. Rees; E. Pabon; H. Roberts; I. Robertson; S. Roche; C.S. Rollier; R. Romani; Z. Rose; I. Rudiansyah; S. Sabheha; S. Salvador; H. Sanders; K. Sanders; C. Sayce; A.B. Schmid; E. Schofield; G. Screaton; C. Sedik; R.R. Segireddy; B. Selby; I. Shaik; H.R. Sharpe; A. Shea; S. Silk; L. Silva-Reyes; D.T. Skelly; D.J. Smith; D.C. Smith; N. Smith; A.J. Spencer; L. Spoors; E. Stafford; I. Stamford; L. Stockdale; D. Stockley; L. Stockwell; M. Stokes; L. Strickland; S. Sulaiman; E. Summerton; Z. Swash; A. Szigeti; A. Alaoui; R. Tanner; I.J. Taylor; K. Taylor; U. Taylor; R. te Water Naude; A. Themistocleous; M. Thomas; T. Thomas; A. Thompson; K. Thompson; V. Thornton-Jones; L. Tinh; S. Tonks; J. Towner; N. Tran; J.A. Tree; A. Truby; C. Turner; R. Turner; M. Ulaszewska; R. Varughese; D. Verbart; M.K. Verheul; I. Vichos; L. Walker; M.E. Wand; B. Watkins; J. Welch; A. West; C. White; R. White; P. Williams; M. Woodyer; A.T. Worth; D. Wright; T. Wrin; X.L. Yao; D.A. Zbarcea; D. Zizi

Lancet (London, England) (2020) - Comments
doi: 10.1016/s0140-6736(20)32466-1 issn: 0140-6736 pubmed: 33220855 issn: 1474-547x doi: 10.2903/j.efsa.2012.2904 issn: 1831-4732

Maheshi N Ramasamy, Angela M Minassian, Katie J Ewer, Amy L Flaxman, Pedro M Folegatti, Daniel R Owens, Merryn Voysey, Parvinder K Aley, Brian Angus, Gavin Babbage, Sandra Belij-Rammerstorfer, Lisa Berry, Sagida Bibi, Mustapha Bittaye, Katrina Cathie, Harry Chappell, Sue Charlton, Paola Cicconi, Elizabeth A Clutterbuck, Rachel Colin-Jones