Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein.
Journal of Biological Chemistry (2013) - Comments
doi: 10.1074/jbc.A112.403048  pubmed: 23720783  pmc: PMC3656318  issn: 1083-351X 

Lei Liu, Anirudh Arun, Lakia Ellis, Carina Peritore, Gizem Donmez